Product Data Sheet
Aminooxy-PEG3-azide
Catalog No. A42671
Aminooxy-PEG3-azide is a non-cleavable, three-unit PEG linker primarily used for the synthesis of antibody-drug conjugates (ADCs) and as a PEG-based linker in PROTAC development. This compound features an azide functionality that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a versatile tool for chemical biology applications.
Chemical Information
| Catalog Num | A42671 |
|---|---|
| M. Wt | 234.25 |
| Formula | C8H18N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1306615-51-9 |
| Synonyms | |
| SMILES | NOCCOCCOCCOCCN=[N+]=[N-] |
Biological Activity
| Description | Aminooxy-PEG3-azide is a non-cleavable, three-unit PEG linker primarily used for the synthesis of antibody-drug conjugates (ADCs) and as a PEG-based linker in PROTAC development. This compound features an azide functionality that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a versatile tool for chemical biology applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
