Product Data Sheet

Propargyl-C1-NHS ester

Catalog No. A42705

main product photo
Propargyl-C1-NHS ester is a non-cleavable linker specifically designed for antibody-drug conjugation (ADC). This reagent features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its applications are significant in bioconjugation techniques, enhancing the precision of targeted therapeutics in chemical biology research.
Chemical Information
Catalog NumA42705
M. Wt195.17
FormulaC9H9NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.132178-37-1
Synonyms
SMILESC#CCCC(ON1C(CCC1=O)=O)=O
Biological Activity
DescriptionPropargyl-C1-NHS ester is a non-cleavable linker specifically designed for antibody-drug conjugation (ADC). This reagent features an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its applications are significant in bioconjugation techniques, enhancing the precision of targeted therapeutics in chemical biology research.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.