Product Data Sheet

H-Glu-OtBu

Catalog No. A42707

main product photo
H-Glu-OtBu is a non-cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound facilitates stable attachment between antibodies and drug moieties, enhancing the efficacy and targeting of ADCs in therapeutic applications. Additionally, H-Glu-OtBu serves as an alkyl chain-based linker in the development of PROTACs, enabling the targeted degradation of proteins. Its versatile functionality makes it an essential reagent in chemical research and drug development.
Chemical Information
Catalog NumA42707
M. Wt203.24
FormulaC9H17NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.45120-30-7
Synonyms
SMILESN[C@@H](CCC(O)=O)C(OC(C)(C)C)=O
Biological Activity
DescriptionH-Glu-OtBu is a non-cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound facilitates stable attachment between antibodies and drug moieties, enhancing the efficacy and targeting of ADCs in therapeutic applications. Additionally, H-Glu-OtBu serves as an alkyl chain-based linker in the development of PROTACs, enabling the targeted degradation of proteins. Its versatile functionality makes it an essential reagent in chemical research and drug development.
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