Bis-PEG25-NHS ester
Catalog No. A42721

Bis-PEG25-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras) and antibody-drug conjugates (ADCs). Featuring a cleavable NHS ester moiety, this compound enables precise conjugation and release of biomolecules, facilitating targeted therapeutic strategies. Its versatility makes it suitable for a variety of applications in chemical biology and drug development, particularly in enhancing the selectivity and efficacy of therapeutic agents.
Chemical Information
| Catalog Num | A42721 |
|---|---|
| M. Wt | 1413.55 |
| Formula | C62H112N2O33 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2221948-96-3 |
| Synonyms | |
| SMILES | O=C(CCOCCOCCC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O.[24] |
Biological Activity
| Description | Bis-PEG25-NHS ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras) and antibody-drug conjugates (ADCs). Featuring a cleavable NHS ester moiety, this compound enables precise conjugation and release of biomolecules, facilitating targeted therapeutic strategies. Its versatility makes it suitable for a variety of applications in chemical biology and drug development, particularly in enhancing the selectivity and efficacy of therapeutic agents. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


