Product Data Sheet
Azido-PEG5-acid
Catalog No. A42733
Azido-PEG5-acid is a polyethylene glycol (PEG)-based linker designed for PROTAC (Proteolysis Targeting Chimeras) synthesis. This non-cleavable linker facilitates the development of conjugates and antibody-drug conjugates (ADCs) through its azide functionality. Azido-PEG5-acid participates in click chemistry, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing substrates, and can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its versatility makes it valuable for various applications in chemical biology and drug discovery.
Chemical Information
| Catalog Num | A42733 |
|---|---|
| M. Wt | 335.35 |
| Formula | C13H25N3O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1425973-16-5 |
| Synonyms | |
| SMILES | O=C(O)CCOCCOCCOCCOCCOCCN=[N+]=[N-] |
Biological Activity
| Description | Azido-PEG5-acid is a polyethylene glycol (PEG)-based linker designed for PROTAC (Proteolysis Targeting Chimeras) synthesis. This non-cleavable linker facilitates the development of conjugates and antibody-drug conjugates (ADCs) through its azide functionality. Azido-PEG5-acid participates in click chemistry, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing substrates, and can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its versatility makes it valuable for various applications in chemical biology and drug discovery. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
