Product Data Sheet

Propargyl-PEG5-amine

Catalog No. A42735

main product photo
Propargyl-PEG5-amine is a non-cleavable linker utilized in antibody-drug conjugates (ADCs) and PROTAC synthesis. This PEG-based compound features an alkyne functional group, enabling efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Propargyl-PEG5-amine is valuable for researchers developing innovative therapeutic strategies involving targeted protein degradation and selective delivery of cytotoxic agents.
Chemical Information
Catalog NumA42735
M. Wt275.34
FormulaC13H25NO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1589522-46-2
Synonyms
SMILESC#CCOCCOCCOCCOCCOCCN
Biological Activity
DescriptionPropargyl-PEG5-amine is a non-cleavable linker utilized in antibody-drug conjugates (ADCs) and PROTAC synthesis. This PEG-based compound features an alkyne functional group, enabling efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Propargyl-PEG5-amine is valuable for researchers developing innovative therapeutic strategies involving targeted protein degradation and selective delivery of cytotoxic agents.
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SHIPPING AND STORAGE
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