Product Data Sheet

DBCO-​C6-​acid

Catalog No. A42737

main product photo
DBCO-C6-acid is a non-cleavable ADC linker that facilitates the formation of antibody-drug conjugates (ADCs). Its unique DBCO moiety allows for efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent is particularly useful in the synthesis of carmaphycin analogues, enabling targeted delivery of therapeutic agents for enhanced efficacy in research applications related to targeted cancer therapies.
Chemical Information
Catalog NumA42737
M. Wt333.38
FormulaC21H19NO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1425485-72-8
Synonyms
SMILESO=C(CCCCC(O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
Biological Activity
DescriptionDBCO-C6-acid is a non-cleavable ADC linker that facilitates the formation of antibody-drug conjugates (ADCs). Its unique DBCO moiety allows for efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing compounds. This reagent is particularly useful in the synthesis of carmaphycin analogues, enabling targeted delivery of therapeutic agents for enhanced efficacy in research applications related to targeted cancer therapies.
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SHIPPING AND STORAGE
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