Product Data Sheet
Propargyl-PEG3-NHS ester
Catalog No. A42740
Propargyl-PEG3-NHS ester is a PEG-based linker designed for use in the development of PROTACs and antibody-drug conjugates (ADCs). This cleavable linker features an alkyne group, allowing for efficient synthesis through click chemistry. It specifically enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it a valuable tool for researchers in the fields of drug conjugation and targeted protein degradation.
Chemical Information
| Catalog Num | A42740 |
|---|---|
| M. Wt | 313.30 |
| Formula | C14H19NO7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1428629-71-3 |
| Synonyms | |
| SMILES | O=C(ON1C(CCC1=O)=O)CCOCCOCCOCC#C |
Biological Activity
| Description | Propargyl-PEG3-NHS ester is a PEG-based linker designed for use in the development of PROTACs and antibody-drug conjugates (ADCs). This cleavable linker features an alkyne group, allowing for efficient synthesis through click chemistry. It specifically enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it a valuable tool for researchers in the fields of drug conjugation and targeted protein degradation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
