Product Data Sheet

Azido-PEG9-amine

Catalog No. A42755

main product photo
Azido-PEG9-amine is a non-cleavable linker comprising a 9-unit polyethylene glycol (PEG) chain, primarily utilized in the synthesis of antibody-drug conjugates (ADCs). This versatile reagent features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds containing DBCO or BCN groups, making it suitable for applications in PROTAC synthesis and click chemistry.
Chemical Information
Catalog NumA42755
M. Wt482.57
FormulaC20H42N4O9
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1207714-69-9
Synonyms
SMILESNCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Biological Activity
DescriptionAzido-PEG9-amine is a non-cleavable linker comprising a 9-unit polyethylene glycol (PEG) chain, primarily utilized in the synthesis of antibody-drug conjugates (ADCs). This versatile reagent features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with compounds containing DBCO or BCN groups, making it suitable for applications in PROTAC synthesis and click chemistry.
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SHIPPING AND STORAGE
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