Product Data Sheet
Propargyl-PEG5-NHS ester
Catalog No. A42766
Propargyl-PEG5-NHS ester is a cleavable linker primarily used in the synthesis of antibody-drug conjugates (ADCs) and PROTAC molecules. This PEG/alkyl/ether-based compound features an alkyne functionality, facilitating click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing partners. Its versatility makes it suitable for various applications in targeted protein degradation and the development of ADCs, supporting advanced research in drug delivery and molecular biology.
Chemical Information
| Catalog Num | A42766 |
|---|---|
| M. Wt | 401.41 |
| Formula | C18H27NO9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1393330-40-9 |
| Synonyms | |
| SMILES | C#CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O |
Biological Activity
| Description | Propargyl-PEG5-NHS ester is a cleavable linker primarily used in the synthesis of antibody-drug conjugates (ADCs) and PROTAC molecules. This PEG/alkyl/ether-based compound features an alkyne functionality, facilitating click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing partners. Its versatility makes it suitable for various applications in targeted protein degradation and the development of ADCs, supporting advanced research in drug delivery and molecular biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
