Product Data Sheet
Mal-PEG1-Val-Cit-PABC-OH
Catalog No. A42794
Mal-PEG1-Val-Cit-PABC-OH is a cleavable polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This linker facilitates the attachment of cytotoxic agents to antibodies while maintaining stability in circulation. Upon reaching the target site, the linker can be cleaved, releasing the therapeutic payload and enhancing cytotoxic efficacy. This compound is valuable for research applications focusing on ADC development and optimization.
Chemical Information
| Catalog Num | A42794 |
|---|---|
| M. Wt | 574.63 |
| Formula | C27H38N6O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055041-37-5 |
| Synonyms | |
| SMILES | O=C(NC(C=C1)=CC=C1CO)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCN(C2=O)C(C=C2)=O)=O)=O |
Biological Activity
| Description | Mal-PEG1-Val-Cit-PABC-OH is a cleavable polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This linker facilitates the attachment of cytotoxic agents to antibodies while maintaining stability in circulation. Upon reaching the target site, the linker can be cleaved, releasing the therapeutic payload and enhancing cytotoxic efficacy. This compound is valuable for research applications focusing on ADC development and optimization. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
