Product Data Sheet
Tetraethylene glycol monotosylate
Catalog No. A42801
Tetraethylene glycol monotosylate is a versatile cleavable linker primarily utilized in the synthesis of antibody-drug conjugates (ADCs). Its acylhydrazone moiety facilitates targeted drug delivery while enabling controlled release of cytotoxic agents. In addition to ADC applications, this compound can also serve as a linker in the development of proteolysis-targeting chimera (PROTAC) molecules, enhancing the specificity and efficacy of targeted protein degradation studies.
Chemical Information
| Catalog Num | A42801 |
|---|---|
| M. Wt | 348.41 |
| Formula | C15H24O7S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 77544-60-6 |
| Synonyms | Tos-PEG4 |
| SMILES | OCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O |
Biological Activity
| Description | Tetraethylene glycol monotosylate is a versatile cleavable linker primarily utilized in the synthesis of antibody-drug conjugates (ADCs). Its acylhydrazone moiety facilitates targeted drug delivery while enabling controlled release of cytotoxic agents. In addition to ADC applications, this compound can also serve as a linker in the development of proteolysis-targeting chimera (PROTAC) molecules, enhancing the specificity and efficacy of targeted protein degradation studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
