Product Data Sheet

Propargyl-PEG2-NHBoc

Catalog No. A42819

main product photo
Propargyl-PEG2-NHBoc is a cleavable linker designed for use in the synthesis of PROTACs and antibody-drug conjugates (ADCs). This PEG-based linker features an alkyne group, allowing for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its unique properties support robust applications in drug development and targeted protein degradation research, making it a valuable tool for chemical biology studies.
Chemical Information
Catalog NumA42819
M. Wt243.30
FormulaC12H21NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.869310-84-9
Synonyms
SMILESO=C(NCCOCCOCC#C)OC(C)(C)C
Biological Activity
DescriptionPropargyl-PEG2-NHBoc is a cleavable linker designed for use in the synthesis of PROTACs and antibody-drug conjugates (ADCs). This PEG-based linker features an alkyne group, allowing for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its unique properties support robust applications in drug development and targeted protein degradation research, making it a valuable tool for chemical biology studies.
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