Product Data Sheet
N-Boc-4-hydroxy-L-proline methyl ester
Catalog No. A42922
N-Boc-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker for antibody-drug conjugates (ADCs), facilitating the targeted delivery of therapeutic agents. This compound also functions as an alkyl chain-based linker in the synthesis of PROTACs (proteolysis-targeting chimeras), contributing to the modulation of protein degradation pathways. Its utility in both ADC and PROTAC applications makes it valuable for advancing research in targeted therapies and protein regulation.
Chemical Information
| Catalog Num | A42922 |
|---|---|
| M. Wt | 245.27 |
| Formula | C11H19NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 102195-79-9 |
| Synonyms | |
| SMILES | O=C(N1[C@H](C(OC)=O)C[C@H](O)C1)OC(C)(C)C |
Biological Activity
| Description | N-Boc-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker for antibody-drug conjugates (ADCs), facilitating the targeted delivery of therapeutic agents. This compound also functions as an alkyl chain-based linker in the synthesis of PROTACs (proteolysis-targeting chimeras), contributing to the modulation of protein degradation pathways. Its utility in both ADC and PROTAC applications makes it valuable for advancing research in targeted therapies and protein regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
