Product Data Sheet

SPDMB

Catalog No. A42942

main product photo
SPDMB is a glutathione-cleavable linker designed for antibody-drug conjugates (ADCs). This compound enables the selective release of cytotoxic agents within target cells, enhancing therapeutic efficacy while minimizing systemic toxicity. SPDMB is crucial for constructing ADCs in research applications focused on targeted cancer therapies and drug delivery mechanisms.
Chemical Information
Catalog NumA42942
M. Wt340.42
FormulaC14H16N2O4S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2101206-29-3
Synonyms
SMILESCC(SSC1=NC=CC=C1)(C)CC(ON2C(CCC2=O)=O)=O
Biological Activity
DescriptionSPDMB is a glutathione-cleavable linker designed for antibody-drug conjugates (ADCs). This compound enables the selective release of cytotoxic agents within target cells, enhancing therapeutic efficacy while minimizing systemic toxicity. SPDMB is crucial for constructing ADCs in research applications focused on targeted cancer therapies and drug delivery mechanisms.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.