Product Data Sheet

Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2

Catalog No. A42956

main product photo
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable linker specifically designed for the construction of antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic agents upon internalization by target cells, enhancing the therapeutic efficacy and reducing off-target effects. Its application in ADC development supports the advancement of targeted cancer therapies and other biopharmaceutical innovations.
Chemical Information
Catalog NumA42956
M. Wt483.38
FormulaC20H21NO13
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.148579-93-5
Synonyms
SMILESO=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(C=O)C=C2[N+]([O-])=O
Biological Activity
DescriptionMe-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable linker specifically designed for the construction of antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic agents upon internalization by target cells, enhancing the therapeutic efficacy and reducing off-target effects. Its application in ADC development supports the advancement of targeted cancer therapies and other biopharmaceutical innovations.
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SHIPPING AND STORAGE
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