Product Data Sheet
Sulfo-LC-SPDP
Catalog No. A42969
Sulfo-LC-SPDP is a heterobifunctional crosslinker designed for antibody-drug conjugate (ADC) applications. It features a thiol-cleavable moiety that facilitates selective release of the drug component upon exposure to free thiol groups. Its membrane impermeability ensures that the linker remains within the cellular compartments, making it suitable for targeted delivery of therapeutics. This compound is widely utilized in research focusing on ADC development, enabling improved efficacy and specificity in cancer therapy.
Chemical Information
| Catalog Num | A42969 |
|---|---|
| M. Wt | 505.59 |
| Formula | C18H23N3O8S3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 150244-18-1 |
| Synonyms | |
| SMILES | O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCCCNC(CCSSC2=NC=CC=C2)=O |
Biological Activity
| Description | Sulfo-LC-SPDP is a heterobifunctional crosslinker designed for antibody-drug conjugate (ADC) applications. It features a thiol-cleavable moiety that facilitates selective release of the drug component upon exposure to free thiol groups. Its membrane impermeability ensures that the linker remains within the cellular compartments, making it suitable for targeted delivery of therapeutics. This compound is widely utilized in research focusing on ADC development, enabling improved efficacy and specificity in cancer therapy. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
