Product Data Sheet
Gly-Gly-Gly-PEG4-methyltetrazine
Catalog No. A42983
Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable polyethylene glycol (PEG) linker designed for use in antibody-drug conjugates (ADCs). It features a tetrazine moiety that facilitates rapid and selective conjugation through an inverse electron demand Diels-Alder (iEDDA) reaction with trans-cyclooctene (TCO) derivatives. This compound enhances the stability and efficacy of ADCs, making it valuable for targeted delivery of therapeutics in cancer research and other applications in bioconjugation.
Chemical Information
| Catalog Num | A42983 |
|---|---|
| M. Wt | 534.57 |
| Formula | C23H34N8O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2353409-82-0 |
| Synonyms | |
| SMILES | CC1=NN=C(N=N1)C2=CC=C(C=C2)OCCOCCOCCOCCNC(CNC(CNC(CN)=O)=O)=O |
Biological Activity
| Description | Gly-Gly-Gly-PEG4-methyltetrazine is a cleavable polyethylene glycol (PEG) linker designed for use in antibody-drug conjugates (ADCs). It features a tetrazine moiety that facilitates rapid and selective conjugation through an inverse electron demand Diels-Alder (iEDDA) reaction with trans-cyclooctene (TCO) derivatives. This compound enhances the stability and efficacy of ADCs, making it valuable for targeted delivery of therapeutics in cancer research and other applications in bioconjugation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
