Product Data Sheet
Me-Tet-PEG8-Maleimide
Catalog No. A42984
Me-Tet-PEG8-Maleimide is an ADC linker featuring eight polyethylene glycol (PEG) units, designed for applications in antibody-drug conjugate (ADC) development. It incorporates a Tetrazine group capable of engaging in a specific inverse electron demand Diels-Alder (iEDDA) reaction with trans-cyclooctene (TCO) compounds, facilitating targeted drug delivery. Additionally, the maleimide functionality exhibits stability in aqueous conditions, making it suitable for various bioconjugation studies and enhancing drug solubility and circulation time.
Chemical Information
| Catalog Num | A42984 |
|---|---|
| M. Wt | 775.85 |
| Formula | C36H53N7O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2143968-05-0 |
| Synonyms | |
| SMILES | O=C1C=CC(N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(NCC2=CC=C(C3=NN=C(C)N=N3)C=C2)=O)=O)=O |
Biological Activity
| Description | Me-Tet-PEG8-Maleimide is an ADC linker featuring eight polyethylene glycol (PEG) units, designed for applications in antibody-drug conjugate (ADC) development. It incorporates a Tetrazine group capable of engaging in a specific inverse electron demand Diels-Alder (iEDDA) reaction with trans-cyclooctene (TCO) compounds, facilitating targeted drug delivery. Additionally, the maleimide functionality exhibits stability in aqueous conditions, making it suitable for various bioconjugation studies and enhancing drug solubility and circulation time. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
