Product Data Sheet

Mal-PEG2-bis-PEG3-BCN

Catalog No. A43012

main product photo
Mal-PEG2-bis-PEG3-BCN is a cleavable linker designed for use in antibody-drug conjugates (ADCs). Featuring a BCN moiety, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enhancing conjugation efficiency. This reagent is ideal for the development of targeted therapies in cancer research and other applications requiring precise drug delivery mechanisms.
Chemical Information
Catalog NumA43012
M. Wt1246.44
FormulaC61H95N7O20
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2882973-13-7
Synonyms
SMILES[H][C@@]12[C@@](CCC#CCC2)([H])[C@@H]1COC(NCCOCCOCCOCCNC(CCOCC(NC(CCOCCOCCNC(CCN3C(C=CC3=O)=O)=O)=O)COCCC(NCCOCCOCCOCCNC(OC[C@@H]4[C@@]5(CCC#CCC[C@@]54[H])[H])=O)=O)=O)=O
Biological Activity
DescriptionMal-PEG2-bis-PEG3-BCN is a cleavable linker designed for use in antibody-drug conjugates (ADCs). Featuring a BCN moiety, it facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enhancing conjugation efficiency. This reagent is ideal for the development of targeted therapies in cancer research and other applications requiring precise drug delivery mechanisms.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.