Product Data Sheet
3,4-Dibromo-Mal-PEG4-Acid
Catalog No. A43021
3,4-Dibromo-Mal-PEG4-Acid is a site-specific linker designed for antibody-drug conjugates (ADCs), featuring a dibromomaleimide moiety that enables dual substitution via its two bromine atoms. The carboxylic acid group can react with primary amines in the presence of coupling agents such as EDC and HATU, facilitating the formation of stable amide bonds. Additionally, the hydrophilic PEG4 linker enhances the solubility of the resulting conjugate in aqueous environments, making it suitable for various bioconjugation applications in chemical and biological research.
Chemical Information
| Catalog Num | A43021 |
|---|---|
| M. Wt | 503.14 |
| Formula | C15H21Br2NO8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2434639-17-3 |
| Synonyms | |
| SMILES | O=C(CCOCCOCCOCCOCCN1C(C(Br)=C(C1=O)Br)=O)O |
Biological Activity
| Description | 3,4-Dibromo-Mal-PEG4-Acid is a site-specific linker designed for antibody-drug conjugates (ADCs), featuring a dibromomaleimide moiety that enables dual substitution via its two bromine atoms. The carboxylic acid group can react with primary amines in the presence of coupling agents such as EDC and HATU, facilitating the formation of stable amide bonds. Additionally, the hydrophilic PEG4 linker enhances the solubility of the resulting conjugate in aqueous environments, making it suitable for various bioconjugation applications in chemical and biological research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
