Product Data Sheet
Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me
Catalog No. A43033
Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me is a disaccharide linker that serves as a substrate for the endo-glycosidase Endo-S2. This compound facilitates the site-specific modification of antibodies by enabling the direct transfer to the conserved N-glycosylation site at Asn297 within the Fc domain. Its utility in the synthesis of antibody-drug conjugates (ADCs) supports a range of research applications, particularly in the fields of immunotherapy and biomolecular engineering.
Chemical Information
| Catalog Num | A43033 |
|---|---|
| M. Wt | 656.59 |
| Formula | C25H40N2O18 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2823367-76-4 |
| Synonyms | |
| SMILES | OC[C@@H](O[C@@]1([H])[C@@](N=C(O1)C)([H])[C@H]2O)[C@H]2O[C@@H]([C@@H]([C@H]([C@H]3O)O)O)O[C@@H]3CO[C@]4(O[C@@]([C@@H]([C@H](C4)O)NC(C)=O)([H])[C@H](O)[C@H](O)CO)C(O)=O |
Biological Activity
| Description | Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me is a disaccharide linker that serves as a substrate for the endo-glycosidase Endo-S2. This compound facilitates the site-specific modification of antibodies by enabling the direct transfer to the conserved N-glycosylation site at Asn297 within the Fc domain. Its utility in the synthesis of antibody-drug conjugates (ADCs) supports a range of research applications, particularly in the fields of immunotherapy and biomolecular engineering. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
