Product Data Sheet
Azido-PEG3-Val-Cit-PAB-OH
Catalog No. A43066
Azido-PEG3-Val-Cit-PAB-OH is a cleavable antibody-drug conjugate (ADC) linker designed for targeted therapeutic applications. Featuring an azide functional group, it facilitates bioconjugation using copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. This versatile linker plays a crucial role in the development of ADCs, enhancing their efficacy and therapeutic index in cancer research and treatment.
Chemical Information
| Catalog Num | A43066 |
|---|---|
| M. Wt | 608.69 |
| Formula | C27H44N8O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055024-65-0 |
| Synonyms | |
| SMILES | O=C(N)[C@H](CCCNC(N)=O)N(C([C@H](C(C)C)NC(CCOCCOCCOCCN=[N+]=[N-])=O)=O)C1=CC=C(CO)C=C1 |
Biological Activity
| Description | Azido-PEG3-Val-Cit-PAB-OH is a cleavable antibody-drug conjugate (ADC) linker designed for targeted therapeutic applications. Featuring an azide functional group, it facilitates bioconjugation using copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN moieties. This versatile linker plays a crucial role in the development of ADCs, enhancing their efficacy and therapeutic index in cancer research and treatment. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
