Product Data Sheet
Azido-PEG5-Ala-Ala-Asn-PAB
Catalog No. A43070
Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable linker designed for use in antibody-drug conjugates (ADCs). This 5 unit PEG-based reagent features an azide group that enables its application in click chemistry, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. It is also suitable for strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, facilitating efficient conjugation in the development of targeted therapeutics.
Chemical Information
| Catalog Num | A43070 |
|---|---|
| M. Wt | 697.73 |
| Formula | C30H47N7O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055048-54-7 |
| Synonyms | |
| SMILES | O=C(O)C[C@@H](C(NC1=CC=C(CO)C=C1)=O)NC([C@H](C)NC([C@H](C)NC(CCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)=O |
Biological Activity
| Description | Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable linker designed for use in antibody-drug conjugates (ADCs). This 5 unit PEG-based reagent features an azide group that enables its application in click chemistry, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. It is also suitable for strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, facilitating efficient conjugation in the development of targeted therapeutics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
