Product Data Sheet
LC-SMCC
Catalog No. A43103
LC-SMCC is a versatile ADC linker that facilitates the conjugation of drugs to antibodies, enabling the development of antibody-drug conjugates (ADCs). Its primary mechanism involves the formation of stable thioether bonds through the reaction with thiol groups on the antibody. This compound is crucial for enhancing targeted delivery and efficacy of therapeutic agents while minimizing systemic toxicity, making it an essential tool in cancer research and drug development.
Chemical Information
| Catalog Num | A43103 |
|---|---|
| M. Wt | 447.48 |
| Formula | C22H29N3O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 125559-00-4 |
| Synonyms | Succinimidyl-[4-(N-maleimidomethyl)]-cyclohexane-1-carboxy-(6-amidocaproate) |
| SMILES | O=C(CC1)N(OC(CCCCCNC(C2CCC(CN(C(C=C3)=O)C3=O)CC2)=O)=O)C1=O |
Biological Activity
| Description | LC-SMCC is a versatile ADC linker that facilitates the conjugation of drugs to antibodies, enabling the development of antibody-drug conjugates (ADCs). Its primary mechanism involves the formation of stable thioether bonds through the reaction with thiol groups on the antibody. This compound is crucial for enhancing targeted delivery and efficacy of therapeutic agents while minimizing systemic toxicity, making it an essential tool in cancer research and drug development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
