Product Data Sheet

Ald-Ph-amido-PEG4-propargyl

Catalog No. A43122

main product photo
Ald-Ph-amido-PEG4-propargyl is a non-cleavable polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis. This reagent features an alkyne group that enables its use in click chemistry, specifically the copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application facilitates the stable attachment of therapeutic agents to antibodies, enhancing the efficacy of targeted cancer therapies.
Chemical Information
Catalog NumA43122
M. Wt363.40
FormulaC19H25NO6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1969299-27-1
SynonymsAld-benzyl-amide-PEG4-propargyl
SMILESO=C(NCCOCCOCCOCCOCC#C)C1=CC=C(C=O)C=C1
Biological Activity
DescriptionAld-Ph-amido-PEG4-propargyl is a non-cleavable polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis. This reagent features an alkyne group that enables its use in click chemistry, specifically the copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application facilitates the stable attachment of therapeutic agents to antibodies, enhancing the efficacy of targeted cancer therapies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.