Product Data Sheet
TCO-PEG2-Sulfo-NHS ester-EDC Urea
Catalog No. A43139
TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent featuring an azide group, designed for selective labeling of primary amine-containing biomolecules. The compound incorporates a PEG linker and a sulfo-NHS ester moiety, enhancing solubility in aqueous buffers, facilitating its utility in bioconjugation applications. It enables the covalent attachment of TCO moieties to proteins, antibodies, and other macromolecules, while participating in inverse electron demand Diels-Alder (iEDDA) reactions with tetrazine-containing partners. This reagent is suitable for various research applications, including protein labeling and targeted drug delivery studies.
Chemical Information
| Catalog Num | A43139 |
|---|---|
| M. Wt | 679.78 |
| Formula | C28H49N5O12S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2353409-48-8 |
| Synonyms | |
| SMILES | O=C(NCCOCCOCCC(ON1C(CC(S(=O)(O)=O)C1=O)=O)=O)OC2CC/C=C\CCC2.O=C(NCCCN(C)C)NCC |
Biological Activity
| Description | TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent featuring an azide group, designed for selective labeling of primary amine-containing biomolecules. The compound incorporates a PEG linker and a sulfo-NHS ester moiety, enhancing solubility in aqueous buffers, facilitating its utility in bioconjugation applications. It enables the covalent attachment of TCO moieties to proteins, antibodies, and other macromolecules, while participating in inverse electron demand Diels-Alder (iEDDA) reactions with tetrazine-containing partners. This reagent is suitable for various research applications, including protein labeling and targeted drug delivery studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
