Product Data Sheet
Methyltetrazine-amido-N-bis(PEG4-acid)
Catalog No. A43157
Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent that features an azide group, facilitating bioorthogonal reactions. It contains a methyltetrazine moiety and two carboxylic acid groups, enabling stable covalent bonding with TCO-containing compounds through inverse-electron demand Diels-Alder cycloaddition. This reaction occurs rapidly and with high selectivity, avoiding the need for copper catalysis or elevated temperatures. Additionally, the PEG linker enhances water solubility, while the terminal carboxylic acid can react with primary amines in the presence of coupling agents to form stable amide bonds, making it suitable for various research applications in chemical biology.
Chemical Information
| Catalog Num | A43157 |
|---|---|
| M. Wt | 725.78 |
| Formula | C33H51N5O13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2639395-39-2 |
| Synonyms | |
| SMILES | O=C(CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(O)=O)C(CC1=CC=C(C2=NN=C(C)N=N2)C=C1)=O)O |
Biological Activity
| Description | Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent that features an azide group, facilitating bioorthogonal reactions. It contains a methyltetrazine moiety and two carboxylic acid groups, enabling stable covalent bonding with TCO-containing compounds through inverse-electron demand Diels-Alder cycloaddition. This reaction occurs rapidly and with high selectivity, avoiding the need for copper catalysis or elevated temperatures. Additionally, the PEG linker enhances water solubility, while the terminal carboxylic acid can react with primary amines in the presence of coupling agents to form stable amide bonds, making it suitable for various research applications in chemical biology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
