Product Data Sheet
Hydroxy-PEG10-acid
Catalog No. A43306
Hydroxy-PEG10-acid is a PEG-based non-cleavable linker designed for the synthesis of Antibody-Drug Conjugates (ADCs). Its primary mechanism involves the formation of stable covalent bonds facilitating the attachment of cytotoxic agents to antibodies. This linker enhances the therapeutic efficacy of ADCs by improving solubility and distribution while minimizing systemic toxicity. It finds application in drug development aimed at targeted cancer therapies and other diseases requiring precise delivery systems.
Chemical Information
| Catalog Num | A43306 |
|---|---|
| M. Wt | 530.60 |
| Formula | C23H46O13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2375611-66-6 |
| Synonyms | HO-PEG10-CH2CH2COOH |
| SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
Biological Activity
| Description | Hydroxy-PEG10-acid is a PEG-based non-cleavable linker designed for the synthesis of Antibody-Drug Conjugates (ADCs). Its primary mechanism involves the formation of stable covalent bonds facilitating the attachment of cytotoxic agents to antibodies. This linker enhances the therapeutic efficacy of ADCs by improving solubility and distribution while minimizing systemic toxicity. It finds application in drug development aimed at targeted cancer therapies and other diseases requiring precise delivery systems. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
