Product Data Sheet
Propargyl-PEG4-CH2CO2-NHS
Catalog No. A43437
Propargyl-PEG4-CH2CO2-NHS is an ADC linker that features a propargyl group and an N-hydroxysuccinimidyl (NHS) moiety. This compound facilitates the synthesis of antibody-drug conjugates (ADCs) by enabling selective coupling with amine-containing biomolecules. As a click chemistry reagent, it contains an alkyne functional group, allowing for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing partners. This versatile tool is essential for enhancing the potency and specificity of targeted therapeutics in bioconjugation applications.
Chemical Information
| Catalog Num | A43437 |
|---|---|
| M. Wt | 343.33 |
| Formula | C15H21NO8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2144777-76-2 |
| Synonyms | |
| SMILES | C#CCOCCOCCOCCOCC(ON1C(CCC1=O)=O)=O |
Biological Activity
| Description | Propargyl-PEG4-CH2CO2-NHS is an ADC linker that features a propargyl group and an N-hydroxysuccinimidyl (NHS) moiety. This compound facilitates the synthesis of antibody-drug conjugates (ADCs) by enabling selective coupling with amine-containing biomolecules. As a click chemistry reagent, it contains an alkyne functional group, allowing for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing partners. This versatile tool is essential for enhancing the potency and specificity of targeted therapeutics in bioconjugation applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
