Product Data Sheet
Alkyne-Val-Cit-PAB-PNP
Catalog No. A43448
Alkyne-Val-Cit-PAB-PNP is a cleavable linker designed for antibody-drug conjugates (ADCs). This compound facilitates stable attachment of cytotoxic agents to antibodies while enabling release in the target tissues or cells via specific enzymatic cleavage. Its properties make it suitable for research applications focused on enhancing the efficacy and selectivity of ADCs in cancer therapy and related studies.
Chemical Information
| Catalog Num | A43448 |
|---|---|
| M. Wt | 638.67 |
| Formula | C31H38N6O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2748039-77-0 |
| Synonyms | |
| SMILES | O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC#C)=O)=O)=O)=O |
Biological Activity
| Description | Alkyne-Val-Cit-PAB-PNP is a cleavable linker designed for antibody-drug conjugates (ADCs). This compound facilitates stable attachment of cytotoxic agents to antibodies while enabling release in the target tissues or cells via specific enzymatic cleavage. Its properties make it suitable for research applications focused on enhancing the efficacy and selectivity of ADCs in cancer therapy and related studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
