Product Data Sheet
Azido-PEG4-Ala-Ala-Asn(Trt)-PAB
Catalog No. A43454
Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a cleavable linker specifically designed for antibody-drug conjugates (ADCs). This compound facilitates the conjugation of antibodies to cytotoxic drugs, enhancing targeted delivery in cancer therapy. Its unique structure allows for selective cleavage in tumor environments, leading to effective drug release and improved therapeutic efficacy. Research applications include the development of novel ADCs and the exploration of targeted delivery mechanisms in oncology research.
Chemical Information
| Catalog Num | A43454 |
|---|---|
| M. Wt | 895.01 |
| Formula | C47H58N8O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2055042-67-4 |
| Synonyms | |
| SMILES | O=C(C[C@H](NC([C@H](C)NC([C@H](C)NC(CCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)=O)C(NC1=CC=C(CO)C=C1)=O)NC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4 |
Biological Activity
| Description | Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a cleavable linker specifically designed for antibody-drug conjugates (ADCs). This compound facilitates the conjugation of antibodies to cytotoxic drugs, enhancing targeted delivery in cancer therapy. Its unique structure allows for selective cleavage in tumor environments, leading to effective drug release and improved therapeutic efficacy. Research applications include the development of novel ADCs and the exploration of targeted delivery mechanisms in oncology research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
