Product Data Sheet

RBx-0597

Catalog No. A43519

main product photo
RBx-0597 is a selective inhibitor of Dipeptidyl Peptidase IV (DPP-IV), exhibiting IC50 values of 32 nM, 31 nM, and 39 nM for human, mouse, and rat plasma DPP-IV, respectively. This compound shows promise in the investigation of type 2 diabetes by modulating glucose metabolism and incretin levels, making it a valuable tool for diabetes research and related metabolic studies.
Chemical Information
Catalog NumA43519
M. Wt374.38
FormulaC19H20F2N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.929105-33-9
Synonyms
SMILESO=C(N1[C@@H](C[C@@H](C1)F)C#N)CN[C@@H]2[C@]3([H])[C@@]2([H])CN(C3)C(C4=CC=C(C=C4)F)=O
Biological Activity
DescriptionRBx-0597 is a selective inhibitor of Dipeptidyl Peptidase IV (DPP-IV), exhibiting IC50 values of 32 nM, 31 nM, and 39 nM for human, mouse, and rat plasma DPP-IV, respectively. This compound shows promise in the investigation of type 2 diabetes by modulating glucose metabolism and incretin levels, making it a valuable tool for diabetes research and related metabolic studies.
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