Product Data Sheet

ASP4000 hydrochloride

Catalog No. A43521

main product photo
ASP4000 hydrochloride is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP4), exhibiting an IC50 value of 2.25 nM against human recombinant DPP4. This compound demonstrates significant antihyperglycemic effects, making it valuable in studies related to type 2 diabetes research. Its oral bioavailability and competitive inhibition profile allow for potential applications in understanding DPP4's role in glucose metabolism and diabetes management.
Chemical Information
Catalog NumA43521
M. Wt271.74
FormulaC12H18ClN3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.851389-35-0
Synonyms
SMILESO=C([C@@H]1[C@H]2C[C@H]([C@H](O)C2)N1)N3[C@@H](CCC3)C#N.Cl
Biological Activity
DescriptionASP4000 hydrochloride is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP4), exhibiting an IC50 value of 2.25 nM against human recombinant DPP4. This compound demonstrates significant antihyperglycemic effects, making it valuable in studies related to type 2 diabetes research. Its oral bioavailability and competitive inhibition profile allow for potential applications in understanding DPP4's role in glucose metabolism and diabetes management.
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SHIPPING AND STORAGE
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