Product Data Sheet

ASP8497

Catalog No. A43538

main product photo
ASP8497 is a competitive inhibitor of dipeptidyl peptidase IV (DPP-IV), which plays a critical role in glucose metabolism. This compound effectively reduces blood glucose levels and elevates plasma active GLP-1 and insulin concentrations without inducing hypoglycemia in fasted normal mice. ASP8497 is suitable for research applications focused on antihyperglycemic mechanisms and glucose regulation.
Chemical Information
Catalog NumA43538
M. Wt462.49
FormulaC18H27FN4O7S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.651055-26-4
Synonyms
SMILESCC1(NCC(N2C[C@@H](F)C[C@H]2C#N)=O)CCN(S(=O)(C)=O)CC1.O=C(O)/C=C/C(O)=O
Biological Activity
DescriptionASP8497 is a competitive inhibitor of dipeptidyl peptidase IV (DPP-IV), which plays a critical role in glucose metabolism. This compound effectively reduces blood glucose levels and elevates plasma active GLP-1 and insulin concentrations without inducing hypoglycemia in fasted normal mice. ASP8497 is suitable for research applications focused on antihyperglycemic mechanisms and glucose regulation.
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