Product Data Sheet

Aldose reductase-IN-5

Catalog No. A43610

main product photo
Aldose reductase-IN-5 is a potent inhibitor of aldose reductase (ALR2), a key enzyme involved in the polyol pathway. By inhibiting ALR2, this compound enhances both the inhibitory excitability and antioxidant capacity, making it useful in research focused on delaying the progression of complications associated with diabetes. Its selective action on aldose reductase positions it as a valuable tool for investigations into metabolic disorders and related therapeutic interventions.
Chemical Information
Catalog NumA43610
M. Wt325.32
FormulaC18H15NO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2480090-03-5
Synonyms
SMILESO=C(O)CN1CC(OC2=C(/C=C/C3=CC=C(O)C=C3)C=CC=C12)=O
Biological Activity
DescriptionAldose reductase-IN-5 is a potent inhibitor of aldose reductase (ALR2), a key enzyme involved in the polyol pathway. By inhibiting ALR2, this compound enhances both the inhibitory excitability and antioxidant capacity, making it useful in research focused on delaying the progression of complications associated with diabetes. Its selective action on aldose reductase positions it as a valuable tool for investigations into metabolic disorders and related therapeutic interventions.
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