Product Data Sheet

ADN 138

Catalog No. A43632

main product photo
ADN 138 is an aldose reductase inhibitor that effectively reduces sorbitol levels in diabetic nerves. This compound leads to significant increases in motor nerve conduction velocity (MNCV) and enhances Na+, K+-ATPase activity in nerve tissues. ADN 138 is valuable for research investigating diabetic neuropathy and related complications, providing insights into potential therapeutic strategies for diabetes-induced nerve damage.
Chemical Information
Catalog NumA43632
M. Wt292.67
FormulaC13H9ClN2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.99434-90-9
Synonyms
SMILESO=C(N1)C2(CC1=O)C3=C4N(CCOC4=CC(Cl)=C3)C2=O
Biological Activity
DescriptionADN 138 is an aldose reductase inhibitor that effectively reduces sorbitol levels in diabetic nerves. This compound leads to significant increases in motor nerve conduction velocity (MNCV) and enhances Na+, K+-ATPase activity in nerve tissues. ADN 138 is valuable for research investigating diabetic neuropathy and related complications, providing insights into potential therapeutic strategies for diabetes-induced nerve damage.
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