Product Data Sheet
Propidium monoazide
Catalog No. A43674
Propidium monoazide (PMA) is a cell-impermeant photoreactive DNA-binding dye that selectively targets double-stranded DNA (dsDNA). It effectively prevents the amplification of DNA derived from dead bacteria during polymerase chain reaction (PCR), enhancing both the specificity and sensitivity of PCR assays. Additionally, PMA serves as a click chemistry reagent, containing an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups, facilitating advanced chemical labeling and analysis in research applications.
Chemical Information
| Catalog Num | A43674 |
|---|---|
| M. Wt | 511.49 |
| Formula | C27H32Cl2N6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 91416-20-5 |
| Synonyms | |
| SMILES | [N-]=[N+]=NC1=CC2=C(C3=C([N+](CCC[N+](CC)(CC)C)=C2C4=CC=CC=C4)C=C(N)C=C3)C=C1.[Cl-].[Cl-] |
Biological Activity
| Description | Propidium monoazide (PMA) is a cell-impermeant photoreactive DNA-binding dye that selectively targets double-stranded DNA (dsDNA). It effectively prevents the amplification of DNA derived from dead bacteria during polymerase chain reaction (PCR), enhancing both the specificity and sensitivity of PCR assays. Additionally, PMA serves as a click chemistry reagent, containing an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups, facilitating advanced chemical labeling and analysis in research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
