Product Data Sheet
BD-Oligo
Catalog No. A43695
BD-Oligo is an oligomer-specific fluorescent chemical probe that selectively targets Aβ oligomer assemblies, distinguishing them from monomers and fibrils. Utilizing diversity-directed fluorescent library screening and advanced computational techniques, BD-Oligo enables real-time monitoring of oligomer formation during Aβ peptide fibrillogenesis. Additionally, this probe demonstrates blood-brain barrier permeability, allowing for in vivo staining of Aβ oligomers, making it a valuable tool for studying Alzheimer's disease and related neurodegenerative processes.
Chemical Information
| Catalog Num | A43695 |
|---|---|
| M. Wt | 571.64 |
| Formula | C25H24BCl3F2N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1357578-02-9 |
| Synonyms | |
| SMILES | OC(C(OCC)=CC=C1)=C1/C=C/C2=[N]3C(C(C)=C2)=CC4=CC=C(CCC(OCC(Cl)(Cl)Cl)=O)[N-]4[B+3]3([F-])[F-] |
Biological Activity
| Description | BD-Oligo is an oligomer-specific fluorescent chemical probe that selectively targets Aβ oligomer assemblies, distinguishing them from monomers and fibrils. Utilizing diversity-directed fluorescent library screening and advanced computational techniques, BD-Oligo enables real-time monitoring of oligomer formation during Aβ peptide fibrillogenesis. Additionally, this probe demonstrates blood-brain barrier permeability, allowing for in vivo staining of Aβ oligomers, making it a valuable tool for studying Alzheimer's disease and related neurodegenerative processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
