Product Data Sheet
KMG-301AM
Catalog No. A43704
KMG-301AM is an acetoxymethyl ester of KMG-301 designed as a Mg2+ fluorescent probe targeting mitochondria. Upon accumulation within mitochondria, KMG-301AM is hydrolyzed to the active form, KMG-301, which is selective for Mg2+ detection in intact cells. This compound remains retained in the mitochondria due to the impermeable nature of the mitochondrial membrane, allowing it to reliably indicate variations in mitochondrial Mg2+ concentration and facilitate studies of Mg2+ transport across the mitochondrial membrane in cellular models.
Chemical Information
| Catalog Num | A43704 |
|---|---|
| M. Wt | 526.56 |
| Formula | C30H28N3O6+ |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1372642-77-7 |
| Synonyms | |
| SMILES | O=C1C(C(OCOC(C)=O)=O)=CC(C(C2=CC=C(N(C)C)C=C2O3)=C4C3=C/C(C=C4)=[N+](C)/C)=C5C=CC=CN51 |
Biological Activity
| Description | KMG-301AM is an acetoxymethyl ester of KMG-301 designed as a Mg2+ fluorescent probe targeting mitochondria. Upon accumulation within mitochondria, KMG-301AM is hydrolyzed to the active form, KMG-301, which is selective for Mg2+ detection in intact cells. This compound remains retained in the mitochondria due to the impermeable nature of the mitochondrial membrane, allowing it to reliably indicate variations in mitochondrial Mg2+ concentration and facilitate studies of Mg2+ transport across the mitochondrial membrane in cellular models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
