Product Data Sheet

TP-α

Catalog No. A43758

main product photo
TP-α is a glucagon-selective two-photon fluorescent probe with a dissociation constant (Kd) of 65 μM. This probe directly interacts with glucagon, resulting in a significant enhancement of fluorescence. TP-α selectively stains viable glucagon-secreting α cells within pancreatic islets, facilitating the visualization of their localization, distribution, and availability. It is particularly valuable for applications in diabetes research.
Chemical Information
Catalog NumA43758
M. Wt581.83
FormulaC38H51N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1708978-54-4
SynonymsTPG-456
SMILESCC(C1=CC2=C(C3(CCCC(CN(C(CN(C)C4=CC5=CC=C(C=C5C=C4)C(C)=O)=O)CCCN)(C3CC2)C)C)C=C1)C
Biological Activity
DescriptionTP-α is a glucagon-selective two-photon fluorescent probe with a dissociation constant (Kd) of 65 μM. This probe directly interacts with glucagon, resulting in a significant enhancement of fluorescence. TP-α selectively stains viable glucagon-secreting α cells within pancreatic islets, facilitating the visualization of their localization, distribution, and availability. It is particularly valuable for applications in diabetes research.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.