Product Data Sheet

1954U89

Catalog No. A43965

main product photo
1954U89 is a potent, lipid-soluble inhibitor of dihydrofolate reductase (DHFR) with oral bioavailability. This compound demonstrates significant anticancer activity, making it a valuable tool in cancer research. Its ability to inhibit DHFR provides insights into folate metabolism and therapeutic strategies targeting rapidly proliferating cells.
Chemical Information
Catalog NumA43965
M. Wt283.37
FormulaC16H21N5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.150057-49-1
Synonyms
SMILESCC(N1C(CC)CC)=CC2=C1C=CC3=NC(N)=NC(N)=C23
Biological Activity
Description1954U89 is a potent, lipid-soluble inhibitor of dihydrofolate reductase (DHFR) with oral bioavailability. This compound demonstrates significant anticancer activity, making it a valuable tool in cancer research. Its ability to inhibit DHFR provides insights into folate metabolism and therapeutic strategies targeting rapidly proliferating cells.
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SHIPPING AND STORAGE
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