Product Data Sheet
Cromolyn-d5
Catalog No. A44123
Cromolyn-d5, a deuterium-labeled derivative of Cromolyn, serves as a stable isotope for research applications. As an orally active inhibitor of GSK-3β with an IC50 of 2.0 μM, Cromolyn exhibits significant biological activity as a mast cell stabilizer, effectively inhibiting the release of mediators and regulating bronchial hyperreactivity. Its utility extends to bronchial asthma research, alongside additional effects including anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective properties.
Chemical Information
| Catalog Num | A44123 |
|---|---|
| M. Wt | 473.40 |
| Formula | C23H11D5O11 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2140317-08-2 |
| Synonyms | Cromoglycate-d5; Cromoglicic acid-d5; FPL-670-d5 free acid |
| SMILES | OC(C([2H])([2H])OC1=C2C(C=C(C(O)=O)OC2=CC=C1)=O)([2H])C([2H])([2H])OC3=C4C(C=C(C(O)=O)OC4=CC=C3)=O |
Biological Activity
| Description | Cromolyn-d5, a deuterium-labeled derivative of Cromolyn, serves as a stable isotope for research applications. As an orally active inhibitor of GSK-3β with an IC50 of 2.0 μM, Cromolyn exhibits significant biological activity as a mast cell stabilizer, effectively inhibiting the release of mediators and regulating bronchial hyperreactivity. Its utility extends to bronchial asthma research, alongside additional effects including anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective properties. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
