Product Data Sheet
AR-A014418-d3
Catalog No. A44133
AR-A014418-d3 is a deuterium-labeled analogue of the selective GSK3β inhibitor AR-A014418. It exhibits potent ATP-competitive inhibition with an IC50 of 104 nM and a Ki of 38 nM. This stable isotope form is useful for tracking and quantifying GSK3β activity in biological systems, and it serves as a valuable tool in research focused on cellular signaling, metabolism, and neurodegenerative diseases.
Chemical Information
| Catalog Num | A44133 |
|---|---|
| M. Wt | 311.33 |
| Formula | C12H9D3N4O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1216908-63-2 |
| Synonyms | AR 0133418-d3; GSK 3β inhibitor VIII-d3; AR 014418-d3 |
| SMILES | O=C(NCC1=CC=C(OC([2H])([2H])[2H])C=C1)NC2=NC=C([N+]([O-])=O)S2 |
Biological Activity
| Description | AR-A014418-d3 is a deuterium-labeled analogue of the selective GSK3β inhibitor AR-A014418. It exhibits potent ATP-competitive inhibition with an IC50 of 104 nM and a Ki of 38 nM. This stable isotope form is useful for tracking and quantifying GSK3β activity in biological systems, and it serves as a valuable tool in research focused on cellular signaling, metabolism, and neurodegenerative diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
