Product Data Sheet

CHIR-21208

Catalog No. A44135

main product photo
CHIR-21208 is a highly selective inhibitor of glycogen synthase kinase-3 (GSK-3), a critical regulator in various cellular processes. This compound demonstrates significant potential in the study of neurodegenerative diseases, including Alzheimer's disease, as well as metabolic disorders such as type 2 diabetes. Researchers can utilize CHIR-21208 to explore GSK-3's role in signaling pathways and its implications in disease mechanisms.
Chemical Information
Catalog NumA44135
M. Wt451.41
FormulaC19H20F3N7O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.206275-65-2
Synonyms
SMILESO=C(N)CN(C=1N=C(NCC2=CC=C(C=C2)C(F)(F)F)C=3N=CN(C3N1)C)C(=O)COC
Biological Activity
DescriptionCHIR-21208 is a highly selective inhibitor of glycogen synthase kinase-3 (GSK-3), a critical regulator in various cellular processes. This compound demonstrates significant potential in the study of neurodegenerative diseases, including Alzheimer's disease, as well as metabolic disorders such as type 2 diabetes. Researchers can utilize CHIR-21208 to explore GSK-3's role in signaling pathways and its implications in disease mechanisms.
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SHIPPING AND STORAGE
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