Product Data Sheet

MJ34

Catalog No. A44144

main product photo
MJ34 is a potent inhibitor of glycogen synthase kinase-3 beta (GSK-3β) and alpha (GSK-3α), exhibiting IC50 values of 15.4 nM and 31.5 nM, respectively. This compound is critical for studies investigating the role of GSK-3 in cancer biology, including cellular signaling pathways and disease progression. MJ34’s ability to selectively inhibit these kinases makes it a valuable tool for exploring therapeutic strategies in cancer research.
Chemical Information
Catalog NumA44144
M. Wt315.37
FormulaC19H17N5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2099015-13-9
Synonyms
SMILESNC1=NC=CC(C2=CNC3=NC=C(C=C32)C4=C(CC)C=CC=C4)=N1
Biological Activity
DescriptionMJ34 is a potent inhibitor of glycogen synthase kinase-3 beta (GSK-3β) and alpha (GSK-3α), exhibiting IC50 values of 15.4 nM and 31.5 nM, respectively. This compound is critical for studies investigating the role of GSK-3 in cancer biology, including cellular signaling pathways and disease progression. MJ34’s ability to selectively inhibit these kinases makes it a valuable tool for exploring therapeutic strategies in cancer research.
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