Product Data Sheet

TC-G 24

Catalog No. A44148

main product photo
TC-G 24 is a selective glycogen synthase kinase-3β (GSK-3β) inhibitor, exhibiting an IC50 of 17.1 nM. This compound is capable of crossing the blood-brain barrier, making it valuable for research on various neurological and metabolic disorders, including type 2 diabetes mellitus, stroke, and Alzheimer's disease. TC-G 24 offers a useful tool for investigating the therapeutic potential of GSK-3β modulation in relevant disease models.
Chemical Information
Catalog NumA44148
M. Wt330.73
FormulaC15H11ClN4O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1257256-44-2
Synonyms
SMILESO=[N+](C1=CC=C(C2=NN=C(NC3=CC=C(C)C(Cl)=C3)O2)C=C1)[O-]
Biological Activity
DescriptionTC-G 24 is a selective glycogen synthase kinase-3β (GSK-3β) inhibitor, exhibiting an IC50 of 17.1 nM. This compound is capable of crossing the blood-brain barrier, making it valuable for research on various neurological and metabolic disorders, including type 2 diabetes mellitus, stroke, and Alzheimer's disease. TC-G 24 offers a useful tool for investigating the therapeutic potential of GSK-3β modulation in relevant disease models.
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