Product Data Sheet
Foxy-5
Catalog No. A44174
Foxy-5 is a WNT5A agonist that functions as a mimetic peptide of the WNT5A protein, a key player in non-canonical Wnt signaling pathways. It induces cytosolic free calcium signaling while leaving β-catenin activation unaffected, and has been shown to inhibit the migration and invasion of epithelial cancer cells. Additionally, Foxy-5 effectively reduces metastatic spread in WNT5A-low prostate cancer cells within an orthotopic mouse model, making it a valuable reagent for cancer research and therapeutic investigations.
Chemical Information
| Catalog Num | A44174 |
|---|---|
| M. Wt | 694.77 |
| Formula | C26H42N6O12S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 881188-51-8 |
| Synonyms | |
| SMILES | [C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CCSC)NC=O)=O)CC(O)=O)=O)=O)CS)=O)(C(N[C@@H](CC(C)C)C(O)=O)=O)CCC(O)=O |
Biological Activity
| Description | Foxy-5 is a WNT5A agonist that functions as a mimetic peptide of the WNT5A protein, a key player in non-canonical Wnt signaling pathways. It induces cytosolic free calcium signaling while leaving β-catenin activation unaffected, and has been shown to inhibit the migration and invasion of epithelial cancer cells. Additionally, Foxy-5 effectively reduces metastatic spread in WNT5A-low prostate cancer cells within an orthotopic mouse model, making it a valuable reagent for cancer research and therapeutic investigations. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
