Product Data Sheet

SANT 2

Catalog No. A44262

main product photo
SANT 2 is a potent antagonist of the Hedgehog (Hh) signaling pathway, specifically inhibiting the expression of Gli1. This compound has been shown to induce developmental delays in medaka embryos, making it a valuable tool for studying embryonic development. SANT 2 has significant research applications in various malignancies, including Gorlin syndrome, as well as prostate, pancreatic, and breast cancers, thereby aiding in the exploration of targeted therapies for these conditions.
Chemical Information
Catalog NumA44262
M. Wt479.96
FormulaC26H26ClN3O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.329196-48-7
Synonyms
SMILESClC1=CC=C(NC(C2=CC(OCC)=C(OCC)C(OCC)=C2)=O)C=C1C3=NC4=CC=CC=C4N3
Biological Activity
DescriptionSANT 2 is a potent antagonist of the Hedgehog (Hh) signaling pathway, specifically inhibiting the expression of Gli1. This compound has been shown to induce developmental delays in medaka embryos, making it a valuable tool for studying embryonic development. SANT 2 has significant research applications in various malignancies, including Gorlin syndrome, as well as prostate, pancreatic, and breast cancers, thereby aiding in the exploration of targeted therapies for these conditions.
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