Product Data Sheet
5(6)-CFDA
Catalog No. A44301
5(6)-CFDA is a fluorescent dye that acts through passive diffusion into cells, where it is hydrolyzed by intracellular non-specific lipases into carboxyl fluorescein (CF). The carboxylate group of CF imparts a negative charge, enhancing its retention within cells compared to traditional fluorescein dyes. This property makes 5(6)-CFDA particularly useful for various biological applications such as cell tracking, apoptosis detection, and cellular viability assays in live cell imaging studies.
Chemical Information
| Catalog Num | A44301 |
|---|---|
| M. Wt | 460.39 |
| Formula | C25H16O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 124387-19-5 |
| Synonyms | 5-(6)-Carboxyfluorescein diacetate; CFDA |
| SMILES | CC(OC1=CC=C2C(OC3=C(C=CC(OC(C)=O)=C3)C24C5=CC(C(O)=O)=CC=C5C(O4)=O)=C1)=O.CC(OC6=CC=C7C(OC8=C(C=CC(OC(C)=O)=C8)C79C%10=CC=C(C(O)=O)C=C%10C(O9)=O)=C6)=O |
Biological Activity
| Description | 5(6)-CFDA is a fluorescent dye that acts through passive diffusion into cells, where it is hydrolyzed by intracellular non-specific lipases into carboxyl fluorescein (CF). The carboxylate group of CF imparts a negative charge, enhancing its retention within cells compared to traditional fluorescein dyes. This property makes 5(6)-CFDA particularly useful for various biological applications such as cell tracking, apoptosis detection, and cellular viability assays in live cell imaging studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
